Publications:
Huaqiang Fang H, Bygrave A*, Roth R, Johnson R, Huganir RL (2021). An optimized CRISPR/Cas9 approach for precise genome editing in neurons. eLife.
Graves AR*, Roth R*, Tan H*, Zhu Q*, Bygrave A*, Lopez-Ortega E, Spiegel A, Hong I, Johnson R, Vogelstein J, Tward D, Miller M, Huganir R (2020). Visualizing synaptic plasticity in vivo by large-scale imaging of endogenous AMPA receptors. BioRxiv.
Yong AJH, Tan HL, Zhu Q, Bygrave AM, Johnson RC, Huganir RL (2020). Tyrosine phosphorylation of the AMPA receptor subunit GluA2 gates homeostatic synaptic plasticity. PNAS.
Lin AC, Bygrave AM, de Caligon A, Lee T, Miesenböck G (2014). Sparse, decorrelated odor coding in the mushroom body enhances learned odor discrimination. Nature Neuroscience.
Bygrave AM, Masiulis S, Nicholson E, Berkemann M, Barkus C, Sprengel R, Harrison PJ, Kullmann DM, Bannerman DM, Kätzel D (2016). Knockout of NMDA-receptors from parvalbumin interneurons sensitizes to schizophrenia-related deficits induced by MK-801. Translational Psychiatry.
Boerner T, Bygrave AM, Chen J, Fernando A, Jackson S, Barkus C, Sprengel R, Seeburg PH, Harrison PJ, Gilmour G, Bannerman DM, Sanderson DJ (2017). The group II metabotropic glutamate receptor agonist LY354740 and the D2 receptor antagonist haloperidol reduce locomotor hyperactivity but fail to rescue spatial working memory in GluA1 knockout mice. European Journal of Neuroscience.
Fiuza M, Rostosky CM, Parkinson GT, Bygrave AM, Halemani N, Baptista M, Milosevic I, Hanley JG (2017). PICK1 regulates AMPA receptor endocytosis via direct interactions with AP2 α-appendage and dynamin. J Cell Biol.
Wolff AR, Bygrave AM, Sanderson DJ, Boyden ES, Bannerman DM, Kullmann DM, Kätzel D (2018). Optogenetic induction of the schizophrenia-related endophenotype of ventral hippocampal hyperactivity causes rodent correlates of positive and cognitive symptoms. Scientific Reports.
Bygrave AM, Masiulis S, Kullmann DM, Bannerman DM, Kätzel D. Gene-Environment Interaction in a Conditional NMDAR-Knockout Model of Schizophrenia (2018). Frontiers in Behavioral Neuroscience.
Bygrave AM, Jahans-Price, T, Wolff AR, Sprengel R, Kullmann DM, Bannerman DM, Kätzel D (2019) Hippocampal-prefrontal theta coherence mediates a causal link between the schizophrenia risk gene GRIA1 and aberrant salience. Translational Psychiatry.
