Selected Publications

For a full list of publication, please click here.

Our laboratory is interested in the molecular mechanisms that modulate the communication between neurons in the brain. This modulation is critical for complex processes in the brain, including learning and memory and development. You can find out more about our work by clicking on "Research focus".

Lagerlöf O, Slocomb JE, Hong I, Aponte Y, Blackshaw S, Hart GW, Huganir RL. (2016) The nutrient sensor OGT in PVN neurons regulates feeding. Science. 351(6279):1293-6. PMCID: PMC4817221.
Zhang, Y., Cudmore, R., Lin, D-T., Linden, D., Huganir, R.L. (2015) Visualization of NMDA Receptor-Dependent AMPA Receptor Synaptic Plasticity In Vivo Nature Neuroscience. 18(3): 402-7. PMCID: PMC4339371.
Diering, G., Gustina, A., Huganir, R.L. (2014) PKA-GluA1 coupling via AKAP5 controls AMPA receptor phosphorylation and cell-surface targeting during bidirectional homeostatic plasticity. Neuron. 84(4): 790-805. PMCID: PMC4254581.
Sia, G.M., Clem, R. L., Huganir, R.L. (2013) The human language-associated gene SRPX2 regulates synapse formation and vocalization in mice. Science. 342(6161): 987-91. PMCID: PMC3903157.
Volk, L.J., Bachman, J.L., Johnson, R., Yu. Y., Huganir, R.L. (2013) PKMz is not required for hippocampal synaptic plasticity, learning and memory. Nature. 493(7432): 420-3. PMCID: PMC3830948.
Makuch, L., Volk, L., Anggono, V., Johnson, R., Yu, Y., Duning, K., Kremerskothen, J., Xia, J., Takamiya, K., Huganir, R.L. (2011) Regulation of AMPA Receptor Function by the Memory-Associated Gene KIBRA. Neuron. 71(6): 1022-9. PMCID: PMC3200575.
Clem, R., Huganir, R.L. (2010) Calcium-permeable AMPA receptor dynamics mediate fear memory erasure. Science. 330(6007): 1108-12. PMCID: PMC3001394.
Lin, D.T., Makino, Y., Sharma, K., Hayashi, T., Neve, R., Takamiya, K., Huganir, R.L. (2009) Regulation of AMPA receptor GluR1 subunit extrasynaptic insertion events by 4.1N, phosphorylation and palmitoylation. Nat. Neurosci. 12(7): 879-87. PMCID: PMC2712131.
Steinberg, J.P., Takamiya, K., Shen, Y., Xia, J., Rubio, M.E., Yu, S., Jin, W., Thomas, G.M., Linden, D.J., Huganir, R.L. (2006) Targeting In Vivo Mutations of the AMPA Receptor Subunit GluR2 and its Interacting Protein PICK1 Eliminate Cerebellar Long-Term Depression. Neuron. 49(6):845-60.
Chung, H.J., Steinberg, J.P., Huganir, R.L. and Linden, D.J. (2003) Requirement of AMPA receptor GluR2 phosphorylation for cerebellar long-term depression. Science 300:1751-1755.
Lee, H-K., Takamiya, K., Han, J-S., Man, H., Kim, C.-H., Rumbaugh, G., Yu, S., Ding, L., He, C., Petralia, R.S., Wenthold, R.J., Gallagher, M., and Huganir, R.L. (2003) Phosphorylation of the AMPA receptor GluR1 subunit is required for synaptic plasticity and retention of spatial memory. Cell 112:631-642.
Lee, H.-K., Barbarosie, M., Kameyama, K., Bear, M.F., and Huganir, R.L. (2000) Reversible changes in distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity. Nature 405:955-959.
Dong, H., O'Brien, R.J., Fung, E.T., Lanahan, A.A., Worley, P.F. and Huganir, R.L. (1997) GRIP: a synapticPDZ domain-containing protein that interacts with AMPA receptors. Nature 386:279-284.
Ehlers, M.D., Zhang, S., Bernhardt, J.P. and Huganir, R.L. (1996) Inactivation of NMDA receptors by direct interaction of calmodulin with the NR1 subunit. Cell, 84:745-755.
Ehlers, M.D., Tingley, W.G. and Huganir, R.L. (1995) Regulated subcellular distribution of the NR1 subunit of the NMDA receptor. Science 269:1734-1737.
Ehlers, M.D., Tingley, W.G. and Huganir, R.L. (1995) Regulated subcellular distribution of the NR1 subunit of the NMDA receptor. Science 269:1734-1737.