Elizabeth Gerber

  • Position: Stetler Research Fellow (Psychiatry)

  • Hometown: Baltimore, MD

  • Education:
    • M.D./Ph.D. from Johns Hopkins
    • B.S. from Notre Dame

  • Research Project:

    • Synaptic Plasticity and Metaplasticity in Neuropsychiatric Disease

       

  • Selected Publications:

    Gerber EE, Gallo EM, Fontana SC, Davis EC, Wigley FM, Huso DL, Dietz HC. Integrin Modulating Therapies Prevent Fibrosis and Autoimmunity in Genetic Mouse Models of Scleroderma. Nature. 503(7474),126-30 (2013). PMID: 24107997

    Gerber  EE,* Loeys BL.,* Riegert-Johnson D,* Iqbal S, Whiteman P, McConnell V, Chillakuri CR, Macaya D, Coucke PJ, De Paepe A, Judge DP, Wigley F, Davis EC, Mardon HJ, Handford P, Keene DR, Sakai LY, Dietz HC. Mutations in fibrillin-1 cause congenital scleroderma: stiff skin syndrome. Sci Transl Med. 2(23), 23ra20 (2010). *equal contribution. PMID: 20375004

    Gerber EE and Dietz HC. Chapter 22. Fibrosis: Insights from the Stiff Skin Syndrome. In Varga, J, Denton, C.P., Wigley, F.M. eds. Scleroderma. From Pathogenesis to Comprehensive Management, 1st edition. New York, NY: Springer US; 2012: 267-282.

    Rouf R, MacFarlane EG, Takimoto E, Chaudhary R, Nagpal V, Rainer PP, Bindman JG, Gerber EE, Bedja D, Schiefer C, Miller KL, Zhu G, Myers L, Amat-Alarcon N, Lee DI, Koitabashi N, Judge DP, Kass DA, Dietz HC. Nonmyocyte ERK1/2 signaling contributes to load-induced cardiomyopathy in Marfan mice. JCI Insight. Aug 3;2(15) (2017). PMID: 28768908

    Bjornsson HT,* Benjamin JS,* Zhang L, Weissman J, Gerber EE, Chen YC, Vaurio RG, Potter MC, Hanson KD, Dietz HC. Histone deacetylase inhibition rescues structural and functional brain deficits in a mouse model of Kabuki syndrome. Sci Transl Med. 6(256):256ra135 (2014). PMID: 25273096

    Gallo EM, Loch DC, Habashi JP, Calderon JF, Chen Y, Bedja D, van Erp C, Gerber EE, Parker SJ, Sauls K, Judge DP, Cooke SK, Lindsay ME, Rouf R, Myers L, Ap Rhys CM, Kent KC, Norris RA, Huso DL, Dietz HC. Angiotensin II-Dependent TGFβ signaling Contributes to the Vascular Pathogenesis of Loeys-Dietz syndrome. J Clin Invest. 124(1), 448–460 (2014). PMID: 4355923

    Doyle JJ, Gerber EE, Dietz HC. Matrix-dependent perturbation of TGFβ signaling and disease. FEBS Lett. 586(14), 2003-15 (2012). PMID: 22641039